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During any examination in an OSCE it is important to understand the pathology and reasoning behind each of the signs and symptoms elicited, even if the patient being examined is 'normal'. This article explains how to examine the hand and wrist. It covers the key findings to look for, what each sign means and what conditions it may indicate.
The hand and wrist examination follows the classic musculoskeletal framework of look, feel and move. This is followed by an assessment of function, a focused neurovascular screen (a check of the nerves and blood supply) and a set of special tests. The examination is used to assess rheumatological disease (disease of the joints and connective tissue) such as rheumatoid arthritis (an autoimmune inflammatory arthritis that mainly affects the small joints) and osteoarthritis (wear-related arthritis), as well as peripheral nerve problems such as carpal tunnel syndrome (compression of the median nerve at the wrist).
Contents
Introduction
Wash your hands and put on personal protective equipment if appropriate.
Introduce yourself to the patient and make sure you mention your grade, for example 3rd year medical student/junior doctor/consultant.
Confirm the patient's details, usually using 3 points of identification: full name, date of birth and NHS or hospital number.
Obtain consent for the examination, ensuring to explain what the examination will entail.
Ask the patient if they have any pain anywhere in their hands or wrists before you begin, so that you can be gentle around any tender areas and avoid causing distress.
Expose the patient's arms to above the elbow and position them sitting comfortably with their hands resting on a pillow or examination cushion placed on a table. This supports the joints, relaxes the muscles and allows you to compare both hands side by side.
General Inspection
Begin with a general inspection of the patient and their surroundings, from the end of the bed or standing back from a seated patient. This often gives important clues before you touch the hands.
Look for signs of discomfort and check whether the patient is using mobility aids. Look for any splints, wrist supports or walking sticks nearby that hint at chronic joint disease. The presence of aids and adaptations such as adapted cutlery or jar openers suggests a long-standing loss of hand function.
Scan for clues to the underlying diagnosis elsewhere on the body. One example is the psoriatic plaques (scaly patches of psoriasis, a skin condition) seen in psoriatic arthritis (joint inflammation linked to psoriasis). These are typically on the outer (extensor) surfaces such as the elbows. They would point towards an inflammatory cause of any hand changes you go on to find.
Inspection of the Hands (Look)
With the patient's palms resting facing down on the pillow, inspect the back (dorsum) of each hand carefully, comparing left with right. Look at the skin, nails, joints and overall posture of the hand.
Look for joint swelling and deformity. In rheumatoid arthritis, the synovium (the lining of the joint) becomes inflamed (synovitis). This causes a symmetrical swelling that characteristically affects the metacarpophalangeal (MCP) joints (the knuckles) and proximal interphalangeal (PIP) joints (the middle finger joints). It spares the distal interphalangeal joints (the joints nearest the fingertips). Over time, the inflammation damages the joint capsule and tendons, producing the classic deformities:
- Swan-neck deformity: hyperextension at the PIP joint with flexion at the distal interphalangeal (DIP) joint.
- Boutonnière deformity: flexion at the PIP joint with hyperextension at the DIP joint. It is caused by the central slip (the part of the extensor tendon that attaches to the middle finger bone) rupturing, so the joint "buttonholes" through.
- Z-thumb: fixed flexion of the MCP joint with hyperextension of the interphalangeal joint.
- Ulnar deviation at the MCP joints (the fingers drift towards the little-finger side), and subluxation (partial dislocation) of the MCP joints.
In contrast, osteoarthritis tends to produce bony rather than soft swellings, and characteristically affects the distal joints. Heberden's nodes are bony swellings at the DIP joints, whilst Bouchard's nodes are bony swellings at the PIP joints. These represent osteophytes (new bone formation) at the joint margins, a response to the loss of articular cartilage. Squaring (a square-looking outline) at the base of the thumb is also common, reflecting osteoarthritis of the first carpometacarpal joint (where the thumb meets the wrist).

Image - Heberden's nodes, the bony swellings at the distal interphalangeal joints seen in osteoarthritis of the hand
Creative commons source by Drahreg01 [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)]
Inspect the nails for signs of underlying disease. Nail pitting (small depressions in the nail plate) and onycholysis (separation of the nail from the nail bed) are features of psoriasis and psoriatic arthritis. Splinter haemorrhages (thin red-brown lines under the nail) may indicate vasculitis (inflammation of blood vessel walls) or infective endocarditis (infection of the heart valves and lining). Nailfold infarcts (tiny dead patches of skin at the nail edge) can be a sign of the systemic vasculitis associated with rheumatoid arthritis. Koilonychia (spoon-shaped nails) points to iron deficiency, while leukonychia (white nails) is often due to minor injury but can also be a sign of systemic disease. For example, Terry's nails (most of the nail looks white, with a thin dark tip) and Muehrcke's lines (paired white bands across the nail) are linked to a low albumin, and Terry's nails are also linked to chronic liver disease. Also check for finger clubbing, the loss of the normal angle at the nail bed. It is not a joint sign, but it points to systemic disease that may accompany an arthropathy (joint disease). Examples are suppurative (pus-forming) lung conditions such as bronchiectasis, and inflammatory bowel disease (Crohn's disease and ulcerative colitis).

Image - finger clubbing, with loss of the normal nail-bed angle, a marker of underlying systemic disease
SimpleMed original image, credit 'SimpleMed original'

Image - splinter haemorrhages, fine longitudinal red-brown streaks under the nail that may point to vasculitis or infective endocarditis
SimpleMed original image, credit 'SimpleMed original'
Examine the skin over the dorsum. Look for the scaly, salmon-pink plaques of psoriasis, the tight, shiny, thickened skin of systemic sclerosis (an autoimmune disease that causes skin tightening; tight, shiny finger skin is called sclerodactyly), and any scars from previous surgery such as carpal tunnel release (surgery to relieve pressure on the median nerve). Thin, fragile skin with bruising may suggest long-term corticosteroid use.

Image - well-demarcated scaly plaques of psoriasis; finding these on the skin or nails points to psoriatic arthritis as the cause of any hand joint changes
SimpleMed original image, credit 'SimpleMed original'
Note any localised swellings. A ganglion is a smooth, fluid-filled cyst that arises from a joint capsule or tendon sheath, most often on the dorsum of the wrist. Gouty tophi are firm, chalky-white deposits of urate crystals seen around the small joints in chronic gout (joint inflammation caused by urate crystals). They can ulcerate and discharge. Both are useful pointers to the underlying diagnosis.
Now ask the patient to turn their hands over so the palms face upwards, and inspect the palmar surface. Look for thenar (base of the thumb) and hypothenar (base of the little finger) muscle wasting. Thenar wasting is an important sign of median nerve compression in carpal tunnel syndrome, because the median nerve supplies most of these muscles. Generalised wasting of the small muscles of the hand suggests damage to the T1 nerve root (the first thoracic nerve root, from the spine) or the ulnar nerve.
Look in the palm for Dupuytren's contracture, a thickening and fibrosis of the palmar fascia (the sheet of tissue under the skin of the palm) that produces a palpable cord. It usually draws the ring and little fingers into a fixed flexed position. It is associated with diabetes, alcohol excess, smoking and a family history. Also note any palmar erythema (reddening of the palms), which can be seen in rheumatoid arthritis, pregnancy and chronic liver disease.
Finally, ask the patient to point their fingers towards you so you can inspect the elbows. Look for psoriatic plaques on the extensor surface and rheumatoid nodules (firm subcutaneous lumps) over the olecranon (the bony point of the elbow). Also look for xanthomata (yellowish cholesterol deposits) that signal hyperlipidaemia (high blood fats).
Palpation (Feel)
Before palpating, remind the patient to tell you if anything is tender and watch their face for signs of discomfort throughout.
Assess the temperature of the hands and wrists using the back of your hand, comparing both sides and comparing the hands with the forearms. Warmth over a joint suggests active inflammation (synovitis), as occurs in a rheumatoid flare or septic arthritis, whilst cool, dusky hands may indicate poor peripheral perfusion.
Palpate the radial pulse at the wrist and, if indicated, the ulnar pulse, to confirm an adequate arterial supply to the hand.
Palpate the thenar and hypothenar muscle bulk to confirm any wasting noted on inspection, and palpate the palm for the firm cord of a Dupuytren's contracture.
Feel along the flexor tendons in the palm as the patient flexes and extends the fingers. A palpable nodule that catches and then releases with a snap, sometimes locking the finger in flexion, indicates trigger finger (stenosing tenosynovitis), where a thickened tendon struggles to glide through its pulley.
Systematically palpate the small joints of the hand. Gently squeeze across the MCP joints in one movement and watch the patient's face; tenderness on the MCP squeeze test is a useful early sign of inflammatory arthritis. Then palpate each MCP, PIP and DIP joint with both hands (bimanually), between your thumbs and index fingers. Feel for boggy soft-tissue swelling (soft and spongy, a sign of active synovitis) versus hard bony swelling (osteoarthritic nodes). Palpate the wrist joint line and the anatomical snuffbox (the hollow on the thumb side of the wrist). Tenderness in the snuffbox raises the possibility of a scaphoid fracture (a break in a small wrist bone). This is important because the scaphoid has a precarious blood supply and is at risk of avascular necrosis (bone death from loss of blood supply) if missed.
Movement (Move)
Assess movement actively first (the patient moves themselves), then passively (you move the joint) if active movement is limited or painful. Comparing active and passive movement helps distinguish two kinds of problem. A problem with the muscles, tendons or nerves reduces active movement but passive movement is preserved. A problem within the joint itself reduces both active and passive movement.
Assess active movements by asking the patient to:
- Make a fist and then fully straighten the fingers: this screens finger flexion and extension and is a quick test of overall hand function.
- Extend the wrists by putting the palms together in a "prayer" position, then flex the wrists in a reverse-prayer position to assess wrist flexion and extension.
- Move the wrists from side to side to assess radial and ulnar deviation, the side-to-side movement at the wrist joint.
- Touch the tip of the thumb to the tip of the little finger to test thumb opposition (bringing the thumb across to touch the other fingers). This depends on the median-nerve-supplied thenar muscles and is often impaired in carpal tunnel syndrome.
If active movement is reduced, repeat the movements passively, feeling for any crepitus (a grating sensation that suggests joint surface roughening in osteoarthritis) and noting the range of movement.
Next assess movements against resistance, which doubles as a quick screen of the three main nerves supplying the hand:
- Wrist and finger extension against resistance: tests the radial nerve. Radial nerve weakness causes a wrist drop (the wrist hangs flexed and cannot be lifted).
- Index finger abduction against resistance: tests the ulnar nerve (first dorsal interosseous, a muscle in the web between the thumb and index finger).
- Thumb abduction against resistance, with the thumb pointing up towards the ceiling away from the palm: tests the median nerve (abductor pollicis brevis, the short muscle that lifts the thumb away from the palm).
Assessment of Function
Hand function is what matters most to patients, so it is always assessed. Ask the patient to:
- Demonstrate a power grip by gripping two of your fingers tightly. This tests overall gross hand strength.
- Demonstrate a pincer (precision) grip by pinching your finger between their thumb and index finger. This requires intact median nerve function and fine motor control.
- Perform a practical functional task, such as picking up a small object (e.g. a coin), undoing a button or holding a pen as if to write.
Difficulty with these tasks demonstrates the real-world impact of any deformity, weakness or sensory loss found earlier in the examination, and helps guide the need for occupational therapy (help to manage everyday tasks) and adaptations.
Neurovascular Assessment
A focused neurovascular assessment confirms which nerve, if any, is involved. The three nerves and their sensory territories are:
- Median nerve: the palmar aspect of the thumb, index, middle and radial half of the ring finger. Test sensation over the index finger pulp. Note that the skin over the thenar eminence is supplied by the palmar cutaneous branch (a skin branch of the median nerve), which arises before the carpal tunnel and so is typically spared in carpal tunnel syndrome.
- Ulnar nerve: the little finger and ulnar half of the ring finger. Test sensation over the pulp of the little finger.
- Radial nerve: the dorsum of the hand over the first web space (the skin between the thumb and index finger). Test sensation over the dorsal first web space.
Assess light touch sensation in each territory, comparing both hands and asking the patient to confirm that the touch feels the same on each side. Reduced or altered sensation in one nerve's territory points to damage to that nerve. A "glove" distribution of sensory loss (the whole hand, like a glove) suggests a peripheral neuropathy (damage to the nerves of the limbs), such as that seen in diabetes.
For the motor assessment, the movements against resistance described above already screen each nerve: thumb abduction (median), finger abduction (ulnar) and wrist/finger extension (radial).
Finally, confirm the vascular supply with the capillary refill time: press on a fingertip for five seconds and release; colour should return in less than two seconds. A prolonged refill time suggests impaired peripheral perfusion.
Special Tests
Special tests are performed if the history or examination suggests a specific diagnosis, most commonly carpal tunnel syndrome (median nerve compression at the wrist) or an ulnar nerve lesion.
Tinel's test assesses for median nerve compression. Tap (lightly percuss) over the carpal tunnel on the palmar aspect of the wrist. The test is positive if this reproduces tingling or paraesthesia in the median nerve distribution (thumb, index, middle and radial half of the ring finger). The mechanism is that mechanical irritation of an already squeezed and over-sensitive nerve triggers abnormal nerve impulses felt as tingling.
Phalen's test also supports a diagnosis of carpal tunnel syndrome. Ask the patient to hold both wrists in full flexion by pressing the backs of their hands together for up to 60 seconds. The test is positive if the patient's symptoms (tingling, burning or numbness in the median nerve distribution) are reproduced. Sustained wrist flexion further reduces the space within the carpal tunnel, increasing pressure on the median nerve.
Froment's test assesses ulnar nerve function, specifically the adductor pollicis muscle (which pulls the thumb towards the palm). Ask the patient to grip a sheet of paper between the thumb and the side of the index finger while you try to pull it away. If the ulnar nerve is impaired, the weak adductor pollicis cannot hold the paper. The patient compensates by flexing the thumb at the interphalangeal joint using flexor pollicis longus (the muscle that bends the thumb tip, supplied by the median nerve). This visible thumb flexion is a positive Froment's sign.
Tinel's and Phalen's tests are useful supporting clues, but neither is definitive. Their reported sensitivity (how often they pick up people who have the condition) and specificity (how often they are negative in people who do not) vary widely between studies. A negative result therefore does not exclude carpal tunnel syndrome, and a positive result does not prove it. Nerve conduction studies (tests of how fast nerves carry signals) are not usually needed when the symptoms are typical. They may be arranged when the diagnosis is uncertain or surgery is being considered, although they can be normal in mild cases.
Completing the Examination
Thank the patient and help them re-dress if needed, then wash your hands.
Summarise your findings to the examiner.
To complete the examination, state that you would perform a full upper limb neurological examination and examine the joint above (the elbow) and the shoulder. If a more widespread arthropathy (joint disease) is suspected, add a GALS screen (a quick screen of gait, arms, legs and spine). You would also assess function further with a formal occupational therapy review, and request relevant investigations such as X-rays of the hands and wrists, blood tests (inflammatory markers, rheumatoid factor and anti-CCP antibodies), and nerve conduction studies if carpal tunnel syndrome or another nerve lesion is suspected.
Quiz
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