1. An Introduction to Infection
- A basic introduction to what an infection
- Understand how a patient might get an infection
- Understand some of the signs of infection
Infection
Infection
Learn the processes and outcomes of infection within the human body and how both the body and medical professionals deals with pathogens.
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- Introduce and explain the concept of an infection mode
- Detail each step of the infection model
- Discuss healthcare acquired infection
3. Bacterial Structure, Classification and Growth
- Connect bacterial walls, capsules, appendages, oxygen use and growth phases with survival, culture behaviour and drug targets.
- What are the different innate barriers to infection?
- How do these barriers work?
- What can damage these barriers or prevent them from working correctly?
- What are the key components in the adaptive immune response?
- What is the function of antigen presenting cells?
- What are MHCs and why are they important?
- Why are T-helper cells important and how do they respond to intracellular and extracellular microbes?
7. Gram Staining and Investigative Techniques
- Understand the investigative techniques used to diagnose a patient's infection and identify the causative micro-organism.
8. Staphylococci and Other Gram-positive Bacteria
- Use morphology, catalase, coagulase, spores and toxin mechanisms to organise the major Gram-positive bacterial groups.
9. Streptococci
- Learn the classification and characteristics of streptococci
- Learn about the virulence factors of Streptococcus pyogenes in particular and how they influence pathogenicity in a clinical context
- More broadly, understand the influence of virulence factors on disease progression in the host.
10. Gram-negative Bacteria: Structure, Entry Routes and Endotoxin
- Relate the Gram-negative envelope and lipopolysaccharide to inflammation, then organise organisms by entry route and biological niche.
11. The Organisms Gram Staining Misses
- Explain why unusual envelopes and intracellular lifestyles evade Gram staining and how that changes diagnostic test selection.
13. Antibiotics
- Be able to outline the commonly used antibiotics and give examples of conditions that they are commonly used to treat
- Be able to describe how each type of antibiotic works
- Be able to discuss the advantages of choosing one antibiotic class over another
- Be able to describe antibiotic resistance
- Be able to outline the commonly used antifungals and antivirals and when they are used
14. Principles of Medical Virology
- Build a reusable model of viral structure, replication, latency, antigenic change, diagnostic methods and selective antiviral targets.
16. Human Immunodeficiency Virus (HIV)
- Understand the epidemiology of HIV
- Learn about the structure, replication and treatment of HIV
- Look at prevention of HIV and associated ethical dilemmas
17. Fungi and Parasites: The Eukaryotic Pathogens
- Compare fungal structure with protozoal and helminth lifecycles to predict selective targets, diagnosis and immune responses.
18. The Immunocompromised Host
- Describe the immune defects associated with immunodeficiency diseases
- Describe the most common primary immunodeficiency diseases and their warning signs
- Understand the basics of management of primary immunodeficiency diseases
- Describe common causes of secondary immunodeficiencies
- Be able to list some common travel related infections, their presentations and the management plan associated with them.
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