During any examination in an OSCE it is important to understand the pathology and reasoning behind each of the signs and symptoms elicited, even if the patient being examined is ‘normal’. This article explains how to perform an eye and vision examination and the key findings you should look for, showing you what each sign means and what conditions it may indicate.
Contents
Introduction
Wash your hands and don personal protective equipment if appropriate.
Introduce yourself to the patient and make sure that you mention your grade e.g. 3rd year medical student/junior doctor/consultant.
Confirm the patient’s details using three points of identification, usually their full name, date of birth and NHS or hospital number.
Obtain consent for the examination, ensuring to explain what the examination will entail. A useful framing is to say you would like to check the patient’s vision, how their eyes move and look at the back of the eyes.
Position the patient sitting comfortably in a chair, ideally facing you at roughly the same eye level for the parts of the examination performed face-to-face.
Ask the patient whether they normally wear glasses or contact lenses, particularly distance glasses, as these will be needed for an accurate assessment of visual acuity (how sharp their central vision is). Also ask if they have any eye pain before you begin.
General Inspection
Begin with a general inspection of the patient and the area around them. Look for obvious clues to the underlying diagnosis. A white stick or guide dog suggests significant visual impairment. Other clues include glasses or contact lens equipment, an eye patch, a magnifier or large-print material, or a prosthetic eye (an artificial eye). These adaptations give an immediate sense of how the patient’s vision affects their daily function.
Inspect the face and eyes for any asymmetry. A facial droop may indicate a previous stroke or a facial nerve palsy (weakness or paralysis of the facial nerve). This matters because incomplete eyelid closure can threaten the cornea (the clear window at the front of the eye). Look at the position of the eyes for any obvious squint (strabismus, where the eyes do not point in the same direction) or proptosis (bulging of the eye), the latter classically associated with thyroid eye disease.
Inspect the eyelids for ptosis (drooping of the upper eyelid). Ptosis can be caused by a third cranial nerve (oculomotor) palsy or Horner’s syndrome (damage to the sympathetic nerve supply to the eye). The associated features help to distinguish them. A third nerve palsy tends to cause a drooping lid, often complete, with a ‘down and out’ eye. The pupil (the black circle at the centre of the eye) is usually dilated when the nerve is compressed, for example by an aneurysm, but it can be spared when the cause is poor blood supply to the nerve. Horner’s syndrome causes a partial ptosis with a constricted pupil.
Look at the eyes themselves for any redness, discharge, abnormal pupil size or shape, and the presence of corneal arcus. Most red eyes are benign and settle on their own, for example with conjunctivitis (inflammation of the thin clear membrane over the white of the eye). However, redness can also be a sign of a sight-threatening problem, such as acute glaucoma (a sudden rise in pressure inside the eye), anterior uveitis (inflammation inside the front of the eye), a corneal ulcer or scleritis (inflammation of the white of the eye). Red flags include reduced vision, moderate to severe pain, headache, sensitivity to light, and an unequal or misshapen pupil. Corneal arcus is a pale ring around the edge of the cornea, seen as a ring around the iris (the coloured part of the eye). It is caused by lipid (fat) deposits. It is common and usually harmless in older people, but under about 45 years of age it can point to raised blood fats (hyperlipidaemia), such as familial hypercholesterolaemia (an inherited condition that causes very high cholesterol).
Visual Acuity
Visual acuity is the sharpness of central vision and is an essential measurement in every eye examination. It is assessed using a Snellen chart (a wall chart of rows of letters that get smaller) positioned at 6 metres from the patient (or at 3 metres using a mirror). If the patient normally wears distance glasses, these should be worn, as you are testing their best corrected vision.
Test each eye separately, asking the patient to cover the other eye and read down the chart until the letters can no longer be made out. Record each eye individually, noting whether glasses were worn.
Visual acuity is recorded as a fraction, for example 6/6. The top number is the distance the patient was from the chart (6 metres). The bottom number is the distance at which a person with normal vision could read that same line. So 6/6 is normal vision, while 6/60 means the patient can only read at 6 metres what a normal-sighted person could read at 60 metres. This is markedly reduced acuity.
If the patient cannot read the top letter of the chart even at 6 metres, move to progressively easier tests. First move the patient to 3 metres, then 1 metre. Next test counting fingers, then hand movements, and finally perception of light. This grading describes exactly how poor the vision is and is important for documentation and for assessing severe disease.
If acuity is reduced, repeat the test with the patient looking through a pinhole. A pinhole allows only the central, most focused rays of light to reach the retina (the light-sensing layer at the back of the eye). If vision improves with a pinhole, the cause is most likely a refractive error (the eye is simply out of focus, correctable with glasses). If it does not improve, this points towards a pathological cause such as cataract (clouding of the lens), macular disease (disease of the macula, the central part of the retina) or optic nerve pathology.
Image - A Snellen chart, used to assess distance visual acuity. The patient reads down the chart at a set distance, and acuity is recorded as a fraction such as 6/6
Creative commons source by Jeff Dahl [CC BY-SA 3.0 (https://creativecommons.org/licenses/by-sa/3.0)]
Near vision should also be assessed, using a near reading chart held at a comfortable reading distance with the patient wearing any reading glasses. Reduced near vision with preserved distance vision is common in presbyopia, the age-related loss of accommodation (the eye’s ability to focus on near objects).
Colour Vision
Colour vision is assessed using Ishihara plates. Each plate is made up of coloured dots arranged to form a number. People with normal colour vision can read the number, but it is difficult or impossible to identify for those with a colour vision deficit.
The patient is asked to identify the number on each plate, testing one eye at a time. The first plate is usually a ‘test plate’ that everyone can read, including those with colour blindness. It checks that the patient has understood the task and has adequate acuity to see the dots.
Ishihara plates primarily assess red-green colour discrimination. Reduced performance in a symptomatic eye may support acquired colour impairment from optic nerve disease, such as optic neuritis (inflammation of the optic nerve), even when visual acuity is relatively preserved. Assess red desaturation separately by comparing the same red target between the eyes and asking whether it looks washed out or less vivid on one side. Colour-plate testing and red-target comparison assess different aspects of colour perception; neither alone establishes a diagnosis of optic neuritis.

Image - An Ishihara red-green colour-discrimination plate. People with typical colour vision read 74; people with red-green colour deficiency may read a different number or no number. This plate is not a direct test of red vividness
Creative commons source by Shinobu Ishihara [Public domain]
Pupillary Reflexes
Before testing the reflexes, inspect the pupils at rest for their size, shape and symmetry. Most people have pupils of roughly equal size; a difference between the two is termed anisocoria.
Understanding the light reflex pathway makes interpreting the findings straightforward. The pathway has two limbs. The afferent limb (the incoming side) carries the signal from the retina to the brainstem along the optic nerve when light is shone into an eye. The efferent limb (the outgoing side) carries the signal back to both pupils via the oculomotor nerve (cranial nerve III) and the parasympathetic fibres, causing both pupils to constrict. Crucially, light shone into one eye normally causes both pupils to constrict because the signal crosses to supply both sides.
To test the direct reflex, dim the room lights and shine a pen torch into one pupil from the side. The pupil into which the light is shone should constrict. To test the consensual reflex, shine the light into one eye but watch the opposite pupil, which should also constrict. The direct reflex tests the afferent limb of the eye being lit and the efferent limb of that same eye. The consensual reflex tests the afferent limb of the lit eye and the efferent limb of the other eye.
The swinging light test is used to detect a relative afferent pupillary defect (RAPD), also known as a Marcus Gunn pupil. Move the torch rhythmically from one eye to the other, pausing on each. In a normal response, both pupils stay constricted as the light swings across. If there is a defect in the afferent pathway of one eye, that eye senses less light. Examples are optic neuritis, a central retinal artery occlusion (blockage of the main artery to the retina) and a large retinal detachment (the retina coming away from the back of the eye). When the torch swings onto the affected eye, the reduced afferent signal causes both pupils to paradoxically dilate, because the brain perceives the overall light input has fallen. An RAPD is therefore a sensitive sign of unilateral or asymmetrical optic nerve or retinal disease.
Finally, test the accommodation reflex. Ask the patient to look at a distant point and then quickly switch their gaze to a target held close to their nose. The eyes should converge and the pupils should constrict to bring the near object into focus. The classic abnormality is the Argyll Robertson pupil, which accommodates but does not react to light (‘accommodation-reaction dissociation’), historically associated with neurosyphilis (syphilis affecting the nervous system).
Visual Fields
The visual fields are assessed by confrontation, comparing the patient’s field of vision with your own. Sit directly opposite the patient at about one metre, with your eyes level with theirs.
Test each eye separately. Ask the patient to cover one eye, and cover your own eye that faces it directly (if they cover their right eye, you cover your left) so that you are mapping their field against yours as a reference. Ask the patient to look straight at your nose, then bring a target (such as a moving fingertip or a red-topped hat pin) in from the periphery in each of the four quadrants, asking the patient to say when they first see it. Their field should match yours if your own fields are normal.
The pattern of any visual field loss localises the lesion (the area of damage) along the visual pathway, which is one of the most clinically valuable aspects of the examination:
- A defect in one eye only (a monocular field loss) suggests pathology anterior to the optic chiasm (the point where the two optic nerves cross), in that eye’s optic nerve or retina.
- A bitemporal hemianopia (loss of the outer half of vision in both eyes) is caused by compression at the optic chiasm, classically by a pituitary tumour.
- A homonymous hemianopia (loss of the same side of the visual field in both eyes) is caused by a lesion behind the chiasm, such as a stroke affecting the optic tract, the optic radiation or the occipital cortex.
You should also test for central scotomas (areas of lost vision within the central field) using a red target. These occur in macular and optic nerve disease. Assess for visual inattention (neglect) by holding both hands in the periphery and wiggling the fingers of one or both at random. A patient who consistently misses one side when both are moved together has visual inattention, typically from a parietal lobe lesion on the opposite side.
The blind spot can also be mapped and compared with your own. The physiological blind spot lies just temporal to central vision and corresponds to the optic disc, where the optic nerve leaves the eye and there are no photoreceptors (light-sensing cells). With one of the patient’s eyes covered and your own eye that faces it directly closed, move a small red target horizontally across the field until it disappears for both of you; an enlarged blind spot suggests optic disc swelling, such as in papilloedema (disc swelling caused by raised pressure inside the skull).

Image - Visual field defects mapped to the level of the lesion. A monocular defect localises in front of the chiasm, a bitemporal hemianopia at the chiasm, and a homonymous hemianopia behind it
Image source by As eo [CC BY-SA 4.0]
Eye Movements
Eye movements assess the function of the three cranial nerves that supply the extraocular muscles (the muscles that move the eye): the oculomotor (III), trochlear (IV) and abducens (VI) nerves.
Ask the patient to keep their head still and follow your finger with their eyes only. Move your finger in an ‘H’ pattern to take the eyes through the full range of horizontal and vertical movement. Watch for restriction of movement, misalignment of the two eyes, and nystagmus (involuntary rhythmic oscillation of the eyes). Keep the target far enough away to avoid triggering convergence, and ask the patient to report any pain on eye movement, which is a characteristic feature of optic neuritis.
Throughout, ask the patient to report any double vision (diplopia) and note the direction of gaze in which it is worst, as this helps identify the affected muscle and nerve. The characteristic nerve palsies are:
- Sixth nerve (abducens) palsy: the affected eye cannot abduct (turn outwards), as the lateral rectus (the muscle that pulls the eye outwards) is paralysed, producing horizontal diplopia worse on looking to that side.
- Fourth nerve (trochlear) palsy: weakness of the superior oblique (a muscle that helps turn the eye down and in) causes vertical diplopia that is worst on looking down and in, such as when reading or descending stairs, and the patient may tilt their head to compensate.
- Third nerve (oculomotor) palsy – produces the classic ‘down and out’ eye with ptosis, because the muscles that elevate, adduct and depress the eye are weak. A fixed dilated pupil in this setting is concerning, as it suggests a compressive cause such as a posterior communicating artery aneurysm, which is a surgical emergency.
Screen for a squint (strabismus) first with the corneal light reflex (Hirschberg) test: shine a pen torch towards both eyes and check that the reflection sits in the same, central position on each cornea. A reflex that is off-centre in one eye indicates that eye is misaligned. Then confirm with the cover test: ask the patient to fixate on a target, cover one eye, and watch the uncovered eye. If it moves to take up fixation (to look at the target), the eyes are misaligned even when both are open: this is a manifest squint (heterotropia).
Fundoscopy
Fundoscopy (ophthalmoscopy) allows direct examination of the retina, optic disc and retinal vessels. It is best performed in a darkened room. Dilating the pupil with a mydriatic (a drug that widens the pupil) such as tropicamide gives a much better view. In an OSCE you would state your intention to do this and check for contraindications first. The main risk is that dilating the pupil can precipitate acute angle-closure glaucoma (a sudden rise in eye pressure when fluid cannot drain) in people with a shallow front chamber of the eye, usually those over 60 years old or long-sighted.
Begin by assessing the red reflex from about an arm’s length away, looking through the ophthalmoscope at each pupil. The reflex is light reflected from the fundus (the back of the inside of the eye) and seen through the pupil. Blood in the underlying choroidal circulation beneath the retina (the choroid is the blood-rich layer behind the retina) contributes its red-orange colour. The hue varies with pigmentation, so assess clarity and symmetry between the eyes. Absence of the reflex or a dark interruption suggests an opacity in the visual axis (something cloudy in the path of light through the eye), such as a cataract or vitreous haemorrhage (bleeding into the jelly that fills the eye). In children, a white reflex (leukocoria) requires urgent assessment because it can indicate retinoblastoma (a rare type of eye cancer that can affect young children) or a congenital cataract.
Then move in close, following a retinal vessel back towards the optic disc. Assess the disc’s colour, margins and central cup. A swollen disc with blurred margins needs its cause to be established. When the cause is raised intracranial pressure (raised pressure inside the skull), the swelling is called papilloedema, but other local or general conditions can also swell the disc. A pale disc indicates optic atrophy (wasting of the optic nerve). An enlarged, deeply excavated cup is seen in glaucoma (damage to the optic nerve, usually from raised pressure inside the eye).
Examine the retinal vessels and the retinal background, then ask the patient to look directly at the light to bring the macula into view. Important findings include the following. Diabetic retinopathy (damage to the retina caused by diabetes) shows microaneurysms (tiny bulges in capillary walls), dot-and-blot haemorrhages, hard exudates (yellow fatty deposits) and neovascularisation (growth of new, fragile vessels). Hypertensive retinopathy (damage to the retina caused by high blood pressure) shows arteriovenous nipping (veins squeezed where arteries cross them), flame haemorrhages and cotton-wool spots. Age-related macular degeneration (age-related damage to the macula, which reduces central vision) shows drusen (yellow deposits under the retina) or pigmentary changes.

Image - A fundus photograph of a normal left eye. The optic disc is seen as the pale circular structure, with the retinal vessels radiating from it and the darker macula to the side
Creative commons source by Mikael Häggström [CC0 1.0 (https://creativecommons.org/publicdomain/zero/1.0)]
Completing the Examination
Thank the patient and wash your hands.
Summarise your findings to the examiner.
To complete the examination, suggest that you would perform a full cranial nerve examination and a slit-lamp examination of the front of the eye (a microscope with a bright light). Also suggest formal visual field testing (perimetry) and fundus photography (a photograph of the back of the eye) as appropriate.
You should also state that you would measure the intraocular pressure (the pressure inside the eye) if glaucoma is suspected. You would check a blood pressure and capillary blood glucose / HbA1c (glycated haemoglobin, a measure of average blood sugar over about three months), given the close link between vision and systemic vascular disease. You would refer to ophthalmology (the eye specialty) for any urgent or unexplained findings.
Quiz
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